Major Bleeding Risk in Atrial Fibrillation Patients on Anticoagulation
Primary Reference
Pisters R, et al.
Chest 2010; 138:1093–1100
Patient Parameters
1. Hypertension (Uncontrolled, >160 Systolic)
2. Abnormal Renal Function
Dialysis, transplant, Cr >2.26 mg/dL
3. Abnormal Liver Function
Cirrhosis, bilirubin >2×, AST/ALT >3×
4. Prior Stroke
5. Prior Major Bleeding
Or predisposition to bleeding
6. Labile INR
TTR <60% or unstable/high INRs
7. Age > 65
8. Drugs (Antiplatelets, NSAIDs)
9. Alcohol (≥8 drinks/week)
Analysis Required
Enter patient parameters to calculate bleeding risk assessment.
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Points
Bleeding Risk Assessment
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Risk Category
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Annual Major Bleed Rate
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Low 0–1Moderate 2High ≥3
Score Breakdown
Clinical Implication
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References & Original Research ↕ Hover to expand
1
Pisters R, Lane DA, Nieuwlaat R, et al.A novel user-friendly score to assess 1-year risk of major bleeding in AF patients. Chest 2010;138:1093–1100. View ↗
2
Lip GYH, et al.HAS-BLED validation and clinical application. J Am Coll Cardiol 2011;57:173–180. View ↗